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Ion Exchange

Ion exchange chromatography (IEC) is based on electrostatic interaction between a charged molecule and an oppositely charged stationary phase. Depending on the type of charge, one discriminates between anion (AEC) and cation exchange chromatography (CEC). Your molecule binds at low salt concentration, while desorption is effected by increasing salt concentration. Ion exchange ligands are classified as either strong or weak, depending on their charge as a function of pH. IEC is a versatile and extensively used tool in downstream processing, and we contribute with a variety of weak and strong AEC and CEC monolithic columns.

  • QA
  • DEAE
  • EDA for IEX
  • SO3