CIM® r-Protein A-8 mL tube is a cylindrical-shaped monolithic column with a column volume of 8 mL. It is encased in a specially designed housing and is supplied ready to use. CIM® r-Protein A-8 mL is intended for purifications at preparative scale. The r-Protein A (recombinant protein A produced in E. coli) is an affinity ligand, used for fast, highly efficient purification of the immunoglobulin G. The Fc portion of antibodies (IgG class) is bound to the r-Protein A without affecting the antigen binding. In an alternative application, the r-Protein A can be used as a platform for binding specific antibodies with their consequent crosslinking. Using this approach, you can prepare your monolithic affinity column for capturing antigens for specific antibodies.
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