CIM® r-Protein L-1 mL tube is a cylindrical-shaped monolithic column with a column volume of 1 mL. It is encased in a specially designed housing and is supplied ready to use. CIM® r-Protein L-1 mL is intended for initial screening, method development, and purifications at laboratory scale. It enables you to develop robust methods that are easily scalable. The r-Protein L (recombinant protein L produced in E. coli) is an affinity ligand, used for fast, highly efficient purification of different immunoglobulins. In contrast to the protein A and protein G, the r-protein L binds to the kappa light chain of antibodies and as such it can be specifically used for IgG, IgA, and IgM antibodies containing only kappa chains. Species whose antibodies contain almost exclusively lambda chains (bovine, goat, sheep, and horse) will not bind well to the Protein L.
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